Currently located at Johnson and Johnson Laboratories incubator space in San Diego California.

We are a biotech company dedicated to discovering tumor-specific molecular isoforms by using a technique that can be applied broadly across all cancer types and any class of molecular target.

Founded in mid-2015 after several years of research and technology refinement.

Our team is composed of immunoncology, cancer genomics, and bioinformatics scientists from the University of California San Diego.

The platform we have developed uses a proprietary process for identifying tumor-specific mRNA isoforms, enabling tumor-specific therapies, which lowers the risk of toxicity and side effects.

Isommune's goal is to identify tumor-specific mRNA that encodes tumor specific isoforms. These mRNA isoforms are the key to creating tumor-specific antibodies.

Isommune's scientists have already discovered mRNA isoforms with compelling potential as therapeutic targets and currently are in varying stages of validation for each target.

Using Isommune's proprietary bioinformatics platform, large data sets of tumor versus normal transcriptome data is analyzed to provide guidance to our in-house developed high-throughput wet lab process which captures variants.

Captured variants are tumor-specific mRNA and protein isoforms that have broad implications for detecting multiple cancer types and assisting in the delivery of novel therapeutic treatments with transformative potential.

Team

Richard Sánchez, MD, MPH, FAAP CEO for Isommune LLC. Dr. Sánchez is an internationally recognized health care executive specializing in managed care operations, health care policy, and the assessment of emerging technology and pharmacy innovations. He has most recently served as Senior Vice President and Chief Medical Officer at Molina Healthcare and Health Choice. There he managed all of their clinical programs. Dr. Sánchez was responsible for the company’s medical affairs, quality and pharmacy departments’ operations and quality initiatives. Prior to assuming this position in 2015, Dr. Sánchez was chief medical officer for Molina Healthcare of California and Molina Healthcare of Utah. He has 20 years of experience in managed health care, having worked as chief medical officer at Mercy Care Plan (Schaller Anderson), Coventry Health Care, Humana and Blue Cross Blue Shield in New York City. Dr. Sánchez has also provided strategic and tactical leadership to several of the nation’s leading managed care organizations, including: AltaMed, Community Health Plan of Washington, Family Health Plan of Chicago, Aloha Care, U Care of Minnesota, Health Integrated, BCBS of North Carolina, McKesson, Iasis Healthcare, Steward Health Choice and AxisPoint. Dr. Sánchez also served eight years as public health commissioner for the city and county of San Francisco, California. Dr. Sánchez received his medical degree from the University of California School of Medicine at San Francisco. He then completed a pediatric residency at Children’s Hospital of Los Angeles. He received a Master of Public Health from the University of California, Berkeley.
James Hoxter Isommune Founder. Mr. Hoxter is a co-founder and President of Isommune LLC, a cancer research and vaccine therapeutics company. Additionally he founded Conversio Health, a nationwide specialty pharmacy focused on patient care, there he provides extensive advisory while serving on the Board of Directors for four different companies. Mr. Hoxter has founded and grown several companies, including Central Coast Medical Supply and Pacific Coast Pharmacy. He has over 35 years of experience of building successful businesses within the healthcare industry. Mr. Hoxter carries extensive medical experience from working within the operating room and as a licensed Respiratory Care Practitioner in neonatal transport/services and acute care. Mr. Hoxter and his wife have initiated non-profit foundations, one of which rebuilds schools serving in underprivileged communities.
Kelly Frazer, PhD CSO for Isommune LLC. Kelly A. Frazer, PhD Isommune Founder and Science Advisory Board Member. Dr. Frazer is a professor and the founding chief of the Division of Genome Information Sciences in the Department of Pediatrics, and Director of UC San Diego’s Institute for Genomic Medicine. Dr. Frazer is an internationally known leader in the field of genomic biology. She obtained her Doctorate of Philosophy in Genetics from University of California San Francisco in 1993. Her research mission is to identify common and rare genetic variants that are associated with human disease in order to functionally assess their role in disease pathogenesis, progression, and prognosis using innovative bioinformatics and computational approaches. Prior to joining UCSD in 2009, Dr. Frazer was Professor of Translational Genomics at the Scripps Research Institute and, previously, Vice President of Genomic Biology at Perlegen Sciences. Dr. Frazer has spent the past 30 years studying various aspects of functional and structural human genomics, and her contributions include pioneering cross-species DNA sequence comparisons between humans and mice, generating the content now publicly available in the “HapMap Phase II,” and developing novel methods for identifying and functionally annotating variants underlying GWAS signals.
Dennis Carson, MD Isommune Founder and Science Advisory Board Member. Emeritus Professor of Medicine, University of California San Diego Moores Cancer Center, Professor of Medicine. Dr. Carson served as the Associate Dean for Health Sciences and the Director of Moores Cancer Center at UCSD for 8 years. Dr. Carson is the cofounder and director of many biotechnical companies pertaining to cancer research as well as being an inventor of 78 US-issued patents. His career has focused on the discovery of new targets in oncology, immunology and infectious diseases. After completing his Doctor of Medicine at Columbia University, and Internal Medicine at University of California San Diego he received post-doctoral training in Immunology and Genetics at the Salk Institute and National Institutes of Health. His specialties span basic and translational research in the fields of autoimmune disorders, hematological cancers, solid tumors, leukemias, lymphomas, breast cancer, melanoma, innate immunity, and vaccine development involving the use of molecular markers. He currently directs a large grant from National Institute of Health in immunology drug discovery and development.
Robert Eversman General Manager and Member of the Business Advisory Council for Isommune LLC. Mr. Eversman began as a laboratory assistant for the Chemistry Department at Lawrence Livermore National Laboratories before going on to receive his Bachelor of Science in Manufacturing Engineering from California Polytechnic State University, San Luis Obispo. He has held positions in project management, new product design and manufacturing, software design and implementation, information technology, and new infrastructure installations. Mr. Eversman has assisted in establishing pharmaceutical and defense related businesses, with his most recent endeavors having an emphasis on finance, analytics, and business operations.
Enabling Life Changing Therapies

Isommune LLC

Contact us

For partnering, investment, or general inquiries

Your message has been sent. Thank you!